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What We're Reading

These pages are updated regularly with interesting articles that we've been reading on the subjects of cancer and, more importantly, disease prevention. We hope that you come back regularly to see what is new.

Breast Cancer
Perioperative COX-2 and β-Adrenergic Blockade Improves Metastatic Biomarkers in Breast Cancer Patients in a Phase-II Randomized Trial Purpose: Translational studies suggest that excess perioperative release of catecholamines and prostaglandins may facilitate metastasis and reduce disease-free survival. This trial tested the combined perioperative blockade of these pathways in breast cancer patients. Experimental Design: In a randomized placebo-controlled biomarker trial, 38 early-stage breast cancer patients received 11 days of perioperative treatment with a β-adrenergic antagonist (propranolol) and a COX-2 inhibitor (etodolac), beginning 5 days before surgery.
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Cancers associated with BRCA1 and BRCA2 mutations other than breast and ovarian Previous studies have reported additional cancers associated with BRCA mutations; however, the type, magnitude of risk, and sex differences remain to be clarified. The purpose of this study was to evaluate...
Sugary, High-Fat Western Diet Tied to Denser Breast Tissue Previous research has linked higher density to increased risk of breast cancer
Actress Rita Wilson Undergoes Double Mastectomy for Breast Cancer LOS ANGELES - Rita Wilson, the actress and wife of actor Tom Hanks, said she underwent a double mastectomy and reconstructive surgery after being diagnosed with an invasive form of breast cancer. "I am recovering and most importantly, expected to make a f
Review: In 'The Human Experiment,' We're the Unwitting Guinea Pigs Not long into " The Human Experiment," a scary if scientifically lightweight documentary about our daily exposure to thousands of synthetic chemicals, you realize that its main targets are women. Proceeding through breast cancer statistics, cosmetics ingr
Apps to Track Exercise, Sleep Help Patients Participate in Clinical Trials Steven DeMello, like many people, uses a smartphone to keep a calendar, take notes, create artful photographs and listen to music. Recently, he began using it for a new purpose: to participate in a clinical trial.
Blood Test for Early Cancer Detection | MIT Technology Review Everything about China is big, including its cancer problem. In some wealthier cities, like Beijing, cancer is now believed to be the most frequent killer. Air pollution, high rates of smoking, and notorious "cancer villages" scarred by industrial polluti
When Whole Genome Sequencing Doesn't Give Us the Whole Genome If you're an avid follower of popular science in today's news media, you might have noticed a recurring theme. Genomics is everywhere. On an almost weekly basis, the New York Times, the New Yorker, Forbes and a myriad of other outlets are publishing stori
How to Measure a Medical Treatment's Potential for Harm As we wrote last week, many fewer people benefit from medical therapies than we tend to think. This fact is quantified in a therapy's Number Needed to Treat, or N.N.T., which tells you the number of people who would need to receive a medical therapy in or